Date |
Speaker
streaming video
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Title of the 1o
Journal Paper |
Authors |
year,
journal |
volume:
pages |
food |
Jan 17 UCL 173 |
Cliff |
Scheduling
Organization of your Talk
Seminar Success Guide
Full USD Syllabus for the Seminar course Brain Stress Circuitry: Orexin Connections
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CH Summers |
2024 Handouts
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Jan 24 UCL 173 |
Cliff |
Storytelling is at the Heart of Science
How to chose a paper, What makes a good talk, Guide to Seminar Design
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CH Summers |
2024
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: : |
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Feb 21 UCL 173 |
Cliff Summers |
The role of the orexin system in stress response
Background papers:
W Giardino, L de Lecea 2014 Current Opinion in Neurobiology 29: 103–108 Hypocretin (orexin) neuromodulation of stress and reward pathways
PL Johnson, A Molosh, SD Fitz, WA Truitt, A Shekhar 2012 Progress in Brain Research 198: 133-161 Orexin, stress, and anxiety/panic states |
D Sargin |
2019
Neuropharmacology |
154: 68–78 |
Megan |
Feb 28 UCL 173 |
Megan John
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Oxytocin and orexin systems bidirectionally regulate the ability of opioid cues to bias reward seeking
Background papers:
CS Thomas, A Mohammadkhani, M Rana, M Qiao, C Baimel, SL Borgland, 2024 Neuropsychopharmacology 47: 728-740 Optogenetic stimulation of lateral hypothalamic orexin/dynorphin inputs in the ventral tegmental area potentiates mesolimbic dopamine neurotransmission and promotes reward-seeking behaviours
LW Hung, S Neuner, JS Polepalli, KT Beier, Matthew Wright, JJ Walsh, EM Lewis, L Luo, K Deisseroth, G Dölen, RC Malenka 2017 Science 357: 1406–1411 Gating of social reward by oxytocin in the ventral tegmental area
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G Giannotti F Mottarlini JA Heinsbroek MR Mandel MH James J Peters
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2022,
Translational Paychiatry |
12: 432 1-11 |
Brylie |
Mar 6 UCL 173 |
Morgan Rothschadl |
Selective orexin 1 receptor antagonist SB-334867 aggravated cognitive dysfunction in 3xTg-AD mice
Background papers:
J-E Kang, MM Lim, RJ Bateman, JJ Lee, LP Smyth, JR Cirrito, N Fujiki, S Nishino, DM Holtzman 2009 Science 326: 1005-1007 Amyloid-ß dynamics are regulated by orexin and the sleep-wake cycle
Yi-Ying Li, Kai-Yue Yu, Yu-Jia Cui, Zhao-Jun Wang, Hong-Yan Cai, Ji-Min Cao, Mei-Na Wur 2023 Neurobiology of Aging 124: 71-84 Orexin-A aggravates cognitive deficits in 3xTg-AD mice by exacerbating synaptic plasticity impairment and affecting amyloid ß metabolism |
W-R Gao, X-H Hu, K-Y Yu, H-Y Cai, Z-J Wang, Lei Wang, M-N Wu |
2023
Behavioural Brain Research |
438: 114171: 1–10 |
Cliff |
Mar 27 UCL 173 |
Brylie Hartwig
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Blockade of corticotropin-releasing factor receptor 1 in the central amygdala prevents cocaine-seeking behaviour induced by orexin-A administered to the posterior paraventricular nucleus of the thalamus in male rats
Background papers:
D Rodaros, DA Caruana, S Amir, J Stewart, 2017 Neuroscience 150: 8–13 Corticotropin-releasing factor projections from limbic forebrain and paraventricular nucleus of the hypothalamus to the region of the ventral tegmental area
JJ Olney, M Navarro, TE Thiele 2017 Alcholism: Clinical and Experimental Research 41: 551–561 The role of orexin signaling in the ventral tegmental area and central amygdala in modulating binge-like ethanol drinking behavior
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A Matzeu R Martin-Fardon
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2021,
J Psychiatry Neurosci |
589: E459-E471 |
Leighton |
Apr 3 UCL 173 |
Leighton Ledesma
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Amygdalar CB2 cannabinoid receptor mediates fear extinction deficits
promoted by orexin-A/hypocretin-1
Background papers:
I Raïch, J Biel Rebassa, J Lillo, A Cordomi, R Rivas-Santisteban, A Lillo, I Reyes-Resina, R Franco, G Navarro, 2022 International Journal of Molecular Sciences 23: 1–19 Antagonization of ox1 receptor potentiates cb2 receptor function in microglia from appsw/ind mice model
Hye Ji J. Kim 1, Ayat Zagzoog 1, Costanza Ceni, R Ferrisi, N Janz, RB Laprairie 2023 Brain Sciences 182: 1574–1588 Dual cannabinoid and orexin regulation of anhedonic behaviour caused by prolonged restraint stresss
O Gunduz-Cinar, KP MacPherson, R Cinar, J Gamble-George, K Sugden, B Williams, G Godlewski, TS Ramikie, AX Gorka, SO Alapafuja, SP Nikas, A Makriyannis9, R Poulton10, S Patel4, AR Hariri, A Caspi, TE Moffitt, G Kunos, A Holmes1 2013 Molecular Psychiatry 18: 813-823 Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity
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M Ten-Blanco A Flores I Pereda-Perez F Piscitelli C Izquierdo-Luengo L Cristino J Romero Cecilia J Hillard R Maldonado V Di Marzo F Berrendero
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2024,
Biomedicine & Pharmacotherapy |
149: 112925: 1-12 |
Morgan |
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Brain Stress Circuitry: Orexin Connections Take Home Messages |
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